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PRISM PHARMA MACHINERY is one of the leading Manufacturers , Supplier and exporter of Fluid Bed Dryer. (High Precision Fluidize Fast Drying & Agglomerating Process Technik) Application & Process: Prism Fluid Bed Processing involves fast drying, cooling and agglomeration of particulate materials. It is ideal for heat sensitive and non heat sensitive products in Pharmaceuticals, Chemicals and Biochemical, Food and Dairy Industries. The Fluid Bed Dryer have a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids. Fines get agglomerated to larger granules particles thus providing large size The machine is designed with correct volume of bowl, air velocity, direction and the temperature of the clean inlet air is maintained throughout the fluidization, retarding, and expansion chambers, filtration area, pitch of the perforations of the plate at the bottom of product container, the leak-proof fluidization space by proper sealing, material of the filters and process controls with electrical & pneumatically. The uniform drying is achieved by exposing the full surface of every particles of the solid mass to the incoming high velocity hot air. Option for the process parameters are controlled by using latest PLC controls with HMI touch screen thus making equipment operationally safe and eliminating the possibility of human error. The process consistency with batch records is maintained for every batch every time. The equipment can be inbuilt CIP system gives a thoroughly cleaned equipment for every batch eliminating contamination of subsequent batches. Salient Features: • Design is cGMP – Current Good Manufacturing Practices compliance. • All contact parts AISI 316 & non contact parts AISI 304. • Single piece construction with Integrated retarding expansion chamber cum filter bag housing • Batch type dryer with available capacity 30 kg to 500 kg. Batch size • Pneumatic Sealing of Filter Bag and Product container by inflatable silicon rubber tube. • Inlet Air handler with Air Filter- Micro, HEPA and Heat Exchanger Steam or Electric. • Exhaust air blower with dynamic balance fan. • Built in Explosion vents and isolation valve protect equipment. • Automatic Temperature controls for Inlet Air and Process cycle time controls. • Washable filter media, FDA approved. • Auto pneumatic filter bag shacking system. • Sampling pot on product container. • Electric and Pneumatic controls panel. Optional Features: • Solid flow detection System. • Advance PLC controls with touch screen • Double scan AHU with Dehumidifier. • Steam or Electric Heater • Exhaust AHU with Filter • Silencer at exhaust blower. • CIP - WIP system. • Explosion proof motor and push button. • Differential Pressure gauge for filter. • Standard model machine with contact parts in S.304 & Non contact parts epoxy painted. Safety Features: • Product Bowl interlocking mechanism. • Automatic Temperature & controls, Process cycle controls. • Explosion flap ensure at retarding chamber. • Safe earthling system for static current. • Air pressure switch installed to ensure pressure is in limit. • Overload relay Protection and Emergency stop button.
Fluid Bed Dryer Machine • Prism Fluid Bed Processing involves fast drying, cooling and agglomeration of particulate materials. It is ideal for heat sensitive and non heat sensitive products in Pharmaceuticals, Chemicals and Biochemical, Food and Dairy Industries. • The Fluid Bed Dryer have a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids. Fines get agglomerated to larger granules particles thus providing large size • The machine is designed with correct volume of bowl, air velocity, direction and the temperature of the clean inlet air is maintained throughout the fluidization, retarding, and expansion chambers, filtration area, pitch of the perforations of the plate at the bottom of product container, the leak-proof fluidization space by proper sealing, material of the filters and process controls with electrical & pneumatically. • The uniform drying is achieved by exposing the full surface of every particles of the solid mass to the incoming high velocity hot air. • Option for the process parameters are controlled by using latest PLC controls with HMI touch screen thus making equipment operationally safe and eliminating the possibility of human error. The process consistency with batch records is maintained for every batch every time. • The equipment can be inbuilt CIP system gives a thoroughly cleaned equipment for every batch eliminating contamination of subsequent batches.  Salient Features : • Design is cGMP - Current Good Manufacturing Practices compliance. • All contact parts AISI 316 & non contact parts AISI 304. • Single piece construction with Integrated retarding expansion chamber cum filter bag housing • Batch type dryer with available capacity 30 kg to 500 kg. Batch size • Pneumatic Sealing of Filter Bag and Product container by inflatable silicon rubber tube. • Inlet Air handler with Air Filter- Micro, HEPA and Heat Exchanger Steam or Electric. • Exhaust air blower with dynamic balance fan. • Built in Explosion vents and isolation valve protect equipment. • Automatic Temperature controls for Inlet Air and Process cycle time controls. • Washable filter media, FDA approved. • Auto pneumatic filter bag shacking system. • Sampling pot on product container. • Electric and Pneumatic controls panel.  Optional Features : • Additional Product container. • Advance PLC controls with touch screen • Double scan AHU with Dehumidifier. • Steam or Electric Heater • Exhaust AHU with Filter • Silencer at exhaust blower. • CIP - WIP system. • Explosion proof motor and push button. • Solid flow detection System. • Differential Pressure gauge for filter. • Standard model machine with contact parts in S.304 & Non contact parts epoxy painted.  Safety Features : • Product Bowl interlocking mechanism. • Automatic Temperature & controls, Process cycle controls. • Explosion flap ensure at retarding chamber. • Safe earthling system for static current. • Air pressure switch installed to ensure pressure is in limit. • Overload relay Protection and Emergency stop button.
Prism Pharma Machinery - is a Gujarat, India based entity, engaged in developing world class range of pharmaceutical machinery to meet present day challenging needs of the clients. We are counted among the trustworthy manufacturers and exporters, assuring best quality machines & timely deliveries. Our offered product array includes Tablet Press, Coating Pan, and many more. These are fabricated in sync with the latest technologies and as per the client provided specifications. Fabricated from superior quality material, our machines are known for their stable operations, low maintenance cost, longer service life, excellent performance, easy installation, and robust construction. The Tablet Presses are available in different models and have a Pre-Compression System which ameliorates the compressibility factor and the Quality of tablet. At Prism Pharma Machinery, we are following a new approach to designing and fabricating our products. In our company, we have installed latest software and related systems / devices, which allow us to ensure precision in every aspect. As per our business policy, we keep a tab on new developments in the segment and introduce them in production of our tablet presses and other machines about which you can know more in our showroom. if you are interested in any of our pharmaceutical machine, then send an inquiry now. We assure to revert quickly.
Prism Pharma Machinery is manufacturer of wet and dry mixers which includes following range: High Shear Mixer Granulator- RMG Mass Mixer Paddle Mixer Blender Ribbon Mixer Blender Sigma Mixer- Z Blade- Dough Mixer Cone Screw - Nauta Mixer Drum Mixer Blender The Paddle Mixer Blender is designed for uniformly wet & dry mixing and blending technology provides the ideal environment for effectively optimum mixing a wide distribution of particle size and bulk densities without segregation of powder, granular, short fibered, moist solids and liquids together with pasty substances up to and including highly viscous masses in the pharmaceutical, chemical, herbal, cosmetic, food, pesticides, detergents, and plastics industries. Optimum mixing achieved by fluidization by combination of defined geometry lifting action with multi zoned, triple paddle stirrer rotor turning about 80 % faster than other mixer and Ribbon blender Additional Information: Item Code: PPB-140 Pay Mode Terms: L/C (Letter of Credit), T/T (Bank Transfer) Port of Dispatch: Any Seaport Production Capacity: 10 Pieces Delivery Time: As Desire by Customer Packaging Details: Export Worthy Wooden Packing
(Roll Compactor - Dry Compaction) Powder Dry Granulation Process. Application & Process : The Roll Compactor machine is used for increased bulk density, making granules, dust free processing and reducing particle size of pharmaceutical ingredients in pharmaceutical industry, in food as well as chemical industry for densification and granulation of powder. The material in form of powder passes through the two counter rotating rolls of roller compactor under very high pressure. As the volume decreases through the region of maximum pressure, the material is formed into a solid compact sheet or flakes of ingredients. These flakes or compact sheet of ingredients are reduced in size to obtain the desired grain size. The machine takes extra care to prevent the generation of fine during this process. New Design Features : • Design is cGMP - Current Good Manufacturing Practices compliance • All Product contact parts AISI 316 & non contact parts AISI 304. • To achieve maximum bulk density and output by various type of rolls. • Available different type of rolls - 1. Plain 2.Corrugated 3.Knurled. • Machine fitted with Corrugated rolls. • Option available for Hydraulically operated Uniform force distribution system can be provided for produce granules equal quality • Option available for the compacting roll can be designed to provide with water cooling system.. • A C Frequency Variable Speed Drive for Auger • Top and bottom scrapper of the roll to scrape off powder sticking on the roll. • Enclosed drive with heavy duty gear box and motor for roll and auger/ feeder. • The hopper and auger/ feeder assembly is lifted by hydraulically for easy cleaning & dismantling. Optional Features : • Option for Uniform force system by hydraulically for Roller. • Optional Water Cooling system for rolls & hopper. • Inline Granulation with Granulator & sifting • PLC Controls with HMI touch screen. • Automatic loading by Vacuum Transfer system. • Flame Proof Electrical. • AC frequency drive for Roller. Safety Features : • Limit switch for chamber, Slip clutch at drive of auger. • Overload relay & Emergency stop.
Ointment - Cream - Tooth Paste- Gel Manufacturing Plant Semi solid manufacturing Plants are ideal tools for the pharmaceutical & cosmetic industries for the production of Ointment, Cream, Lotion, Gel, Tooth Paste & emulsions & homogenization. Application & Process: Ointment manufacturing Plants are ideal tools for the pharmaceutical & cosmetic industries for the production of Ointment, Cream, Lotions, Tooth Paste & other emulsions & homogenization. In operation, • The pre determined water quantity is added to water heating vessel. The steam is supplied and the addition of additives manually and mix at the set temperature. • Then the oil, wax, petroleum jelly is charged to wax phase vessel. The steam and heat are supplied in manufacturing vessel and the additives are added manually and mixed at the set temperature. • Vacuum pump transfers the heated wax and heated water to main manufacturing vessel. The additives are added manually and mixed at the set temperature and also the homogenizer performs emulsification and dispersion • After confirmation of cream / ointment discharge the product is transferred to storage tank using lobe pump. • Keeping the product under slow speed agitation in storage vessel the product is transferred to ointment tube filling machine through ointment transfer pump. Fully automatic Ointment, Cream, Tooth Paste , Gel manufacturing plant consisting of  Pre determined water phase vessel.  Pre determined oil, wax, petroleum jelly phase vessel.  Vacuum Homogenizer Mixer vessel.  Vacuum Pump  Storage vessel  Interconnecting pipeline.  Transfer Pumps (Bump Pump, Lobe Pump & Metering pumps)  Integrated automatic control panel.  Working Platform Design Features :  Design compliance with cGMP • Integrated Cleaning in Place-CIP. • Sterilizing In Place-SIP as an Option.  Batch Size • Available model 50 Liter to 5000 Liter working Capacity.  Materials • Product Contact AISI 316L. • Food Grade silicon rubber for seal.  Water Phase Vessel • Jacket for heating & cooling. • Heating Jacket Pressure (4 bar). • Heating by steam or hot water circulation. • Propeller stirring with top mounting. • Temperature controller & safety pressure Valve. • Bottom discharge with valve.  Wax Phase Vessel • Jacket for heating & cooling. • Heating Jacket Pressure (4 bar). • Heating by steam or hot water circulation. • Propeller stirring with top mounting. • Temperature controller & safety pressure Valve. • Bottom discharge with valve.  Manufacturing Vacuumize Homogenizer Vessel. • Jacket for heating & cooling. • Vacuumize process. • Vessel Inside Pressure (-1 /+2 Bar) • Heating Jacket Pressure (-1 /+6 bar) • Heating by steam or hot water circulation. • Agitator mixer with self pressure Teflon scrapper. • Scrapper cleanly working on both side. • High speed Homogenizer with toothed Rotor - stator type. • RPM sleeplessly with variable speed drive for agitator & Homogenizer. • High shear & pressurization of the homogenizer. • Thus homogenization of high viscosities up to 400.000 mPas. • Homogenizer mounted on lower position in the centre of vessel. • Top lid with motorized top lid for lifting & lowering. • Safety Interlock process with limit switch. • Connection for Vacuum, Charging, Eye glass window, Light glass, CIP, SIP, Pressure gauge & safety valve. • Temperature controller & safety pressure Valve. • Bottom discharge with valve.  Vacuum System • Water Ring Vacuum Pump. • Vacuum gauge & Vacuum relief valve.  Storage Vessel • Skid type storage vessel. • Bottom cone is Jacket for heating.  Inter Connecting Pipe • Inter connecting Pipe line of all vessel for transfer Water, Wax & products. • Recirculation in manufacturing vessels. • Vacuum connecting pipe.  Working Platform • Rigid structure with anti slipping embossed plat. • Made from AISI 304.  Controls & Visualization • Electric Controls with digital display. • Optional PLC Controls with HMI Touch screen. • RPM and Process time entries. • Temperature controls- Heat/cool. • Vacuum start- Stop. • Integrated Data Recording for batch.  Safety Features • Emergency stop button • Safety vacuum relief valve & Indicator Gauge. • Safety Pressure Valve. • Limit switch at top lid
Liquid Syrup Manufacturing Process (Preparation Vessel & Liquid Syrup Manufacturing Plant)  Application & Process : Prism has been designed & manufacturing preparation vessels and has consolidated a process knowledge concerning sterile injectable solution, dispersions, ophthalmic products, syrup and suppositories.  Preparation Vessels & Tank : • Extremely hygienic processing. • Least manual handling. • Design compliance with cGMP • Capacity up to 10, 000 Liter. • Product Contact AISI 316L • Atmospheric, Vacuum or Pressure Operation. • Jacket for heating & cooling. • Vessel Inside Pressure (-1 /+2 Bar) • Heating Jacket Pressure (-1 /+6 bar) • Heating by steam or hot water circulation. • Thermal Insulated. • Mechanicals or Electro polishing of internal surface. • Welded, flanged or hinged type cover • Integrated Cleaning in Place-CIP. • Sterilizing In Place-SIP as an Option. • Portable execution on request. • Validation protocols & Instrumentation celebration.  Variable Speed Agitation : • Agitator can be top or bottom driven or magnetically driven. • Propeller type, Anchor type provided with High speed disperser or rotor-stator homogenizer. • Single or double mechanical seal.  Fully automatic Liquid Syrup Manufacturing Plant consisting of : • Sugar Charging / Transfer System. • Sugar Melting Vessel with mixing stirrer. • Basket Filter & Transfer Pump. • Syrup Manufacturing Vessel with stirrer. • Inline Homogenizer. • Zero Hold up Filter press. • Storage Tank with stirrer. • Interconnecting pipeline. • Transfer Pumps. • Integrated automatic control panel. • Working Platform.  Turn Key Process Line : • For production, filtration, transfer and storage solution. • Pre reparation vessels. • Inline homogenizer. • Inter Connecting Pipe • Solid or sugar Charging System • Working Platform.  Automation available, appropriate for the intended process function, including CIP and SIP : • Controls of all function by PLC Controls with HMI Touch screen. • Level controls by means of capacitance probe or electronic load cells. • Digital indication and controls of all process parameters for Process time, agitator speed, temperature, pressure & level.
Prism Pharma Machinery is one of the leading Manufacturers and Exporters of high quality range of Liquid Syrup Manufacturing Plant . Automatic Oral Syrup Manufacturing Plant Liquid Syrup Manufacturing Process Application & Process: Automatic Oral Syrup Manufacturing Plants are ideal tools for the pharmaceutical industry for the production of Oral Liquids Salient Features: Completely fully automatic liquid / oral manufacturing plant with fully automatic operations and designed as per cGMP – Current Good Manufacturing Practices compliance All contact parts AISI 316 & non contact parts AISI 304. Capacity available from 50 Liters to 10, 000 Liters. Additional Information: Pay Mode Terms: L/C (Letter of Credit), T/T (Bank Transfer) Port of Dispatch: Any Seaport Delivery Time: As Desired by customer Packaging Details: Export worthy wooden packing
Roller Compactors For Dry Granulation Powder Dry Granulation Process:-  Application & Process : • The Roll Compactor machine is used for increased bulk density, making granules, dust free processing and reducing particle size of pharmaceutical ingredients in pharmaceutical industry, in food as well as chemical industry for densification and granulation of powder. • The material in form of powder passes through the two counter rotating rolls of roller compactor under very high pressure. As the volume decreases through the region of maximum pressure, the material is formed into a solid compact sheet or flakes of ingredients. These flakes or compact sheet of ingredients are reduced in size to obtain the desired grain size. The machine takes extra care to prevent the generation of fine during this process.  New Design Features : • Design is cGMP - Current Good Manufacturing Practices compliance • All Product contact parts AISI 316 & non contact parts AISI 304. • To achieve maximum bulk density and output by various type of rolls. • Available different type of rolls - 1. Plain 2.Corrugated 3.Knurled. • Machine fitted with Corrugated rolls. • Option available for Hydraulically operated Uniform force distribution system can be provided for produce granules equal quality • Option available for the compacting roll can be designed to provide with water cooling system.. • A C Frequency Variable Speed Drive for Auger • Top and bottom scrapper of the roll to scrape off powder sticking on the roll. • Enclosed drive with heavy duty gear box and motor for roll and auger/ feeder. • The hopper and auger/ feeder assembly is lifted by hydraulically for easy cleaning & dismantling.  Optional Features : • Option for Uniform force system by hydraulically for Roller. • Optional Water Cooling system for rolls & hopper. • Inline Granulation with Granulator & sifting • PLC Controls with HMI touch screen. • Automatic loading by Vacuum Transfer system. • Flame Proof Electrical. • AC frequency drive for Roller.  Safety Features : • Limit switch for chamber, Slip clutch at drive of auger. • Overload relay & Emergency stop.
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