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Twin Cabinate Bin Washing System : CIP / WIP Closed Clean In Place / Wash in Place System for IBC Bin  Prism Pharma Machinery is pleased to announce our new Machine Development 'Twin Cabinate Bin Washing System' for AUROBINDO APL Healthcare Limited - India.  CIP/ WIP system is useful for cleaning and washing of IBC Bin for inner and outer washing and drying automatically.  Application & Process: • Automatic washing station is consists of closed washing cabinet, washing system with pump, Hot air handling system and PLC controls system with HMI. • Used bin is oriented in the closed cabinet and closed entrance main door for washing. Washing cycle time can be set as per requirements for Plain water, Hot water, Detergent, Distilled water. In auto mode wash cycle works as per set parameter in PLC system. There are nos. of spraying nozzle for washing at all corners & all side walls for outer washing. Top mounting spraying nozzle is fitted with telescopic pneumatic cylinder to wash inner surface of the bin, Inner washing nozzle move upward & downward during washing for completely washing of bin. The cabinet is having drain pot with recirculation of water connection with pump if required then it can be re circulated. After complete washing cycles then bin is dry by passed filter hot air circulation by air handling unit. After drying of Bin on set temperature then released for new batch safe storage. • Closed CIP Bin washing system will be provided with hot water genrator-500 liter, Detergent tank 50lIter, Hot air AHU system, Closed washing cabinet and PLC Controls system with pressure pump and connection for PW and WFI water.  IBC Bin Washing system futures: • Designed as per cGMP principles followed at pharmaceutical corporations globally. • All contact parts AISI 316 & non contact parts AISI 304. • 2 Nos. Closed cabinet type washing system for washing of Bin with water skid, hot air AHU. • 1 No washing booth for vessel and 1 No. washing booth for tray. • WIP & CIP (Wash & Cleaning-In-Place) is a system designed for automatic cleaning by Portable water, Hot Water, detergent, WFI and rinse solutions without major disassembly and assembly work • PLC programmed and automated with interlocks and standard pharma safety procedures. • Principle of high pressure and low volume of water for Washing results in less water consumption and low effluent quantity • The cleaning can be carried out with automated systems is a reliable process that meets the stringent hygiene regulations • Design is completely customizable depending on specific client constraints and requirements • Powerful jets ensure complete internal and external washing of the IBC. • Design optimized to reduce consumption of water and energy. • Specific wash zones for bottom valves and lids. • Telescopic spraying nozzle for inside washing of IBC. • Telescopic hood provides with pneumatic operated for hot air flow inside of the IBC. • One step setting of washing and drying operation. • Water skid Systems can be provided reservoirs for detergent and rinse solutions as well as pumping. • Hot air drying skid- AHU with Double Scan AHU with inside s.s.304 24SWG. And outside powder coated with Pre filter- 10 & 5 micron, Blower-2 hp, heating coil- steam, HEPA 0.3 micron filter. • The washing process consists of several cycles in which rinsing material is recycled through the bin, pumps, valves and other process equipment in the flow system. • All the operation processes take place in sealed pipe line, which is easy to operate saving work and meets high sanitary requirement. • It has advantages as energy-saving, high work efficiency, perfect cleaning effect, operator safety and easy to operate and maintain. • The booth has a provision of locating a single IBC at a time for washing & drying. • Double door design for inlet of IBC Bin and outlet of Bin. • The services such as filtered potable water, hot water, dm / purified water and steam to be provided near the system in the technical area above/next to the machine. • The system is located in-between the unclean & clean wash area as shown above. • The machine has integrated drain pan. • All the services and technical area equipment is located in the booth or on a floor above. The necessary piping & ducting is routed down from openings in the slab. • Flow Rate controls for PW and WFI. • Pressure display for PW, WFI, water for jet and compressed air. • Advance PLC controls with Industrial PC -Touch screen controls with SCADA for records, recipe management and interactive commands. • Swing doors provide convenient loading and removal of bins • Full height glass doors provide complete process monitoring. • Single step operation Load Soiled IBC and 20 to 25 minutes later Remove Washed and dried IBC. • Sample pot at drain. • Option for Hot water generator vessel with temperature controller.
Tablet Press Machine - TabXpress-IV High Speed Double Sided with Pre-Compression Tablet Press Machine- GMP Model  Application & Process : • Prism TabXpress-IV is a High Speed Double Sided Rotary Tablet Compression Press suitable for millennium batch size production. • TabXpress-IV designed in an effort to exceed the highest cGMP requirement and to ensure the most economical and efficient tablet production. The TabXpress -IV features a unique ergonomic design for EASY to Operate, EASY to Fast Changeover, EASY to Clean with minimum down time. The TabXpress is completely separated into three zones i.e. Tablet Compression zone, Machine service zone and Electrical controls zone. The Optional feature of TabXpress-IV machine can provide with Touch Screen Operate Interface with PLC Controls, which is mounted in a separate electric controls cabinet. • The TabXpress-IV Tablet Press is offered in four different models viz. Tooling 45 Stn "D" Type, 55 Stn "B" Type, 69 Stn "BB" Type, 75 Stn "BB" Type. • The Machine Ergonomics Design Concept : • The TabXpress-IV has been completely new designed according to the most modern ergonomic aspects. • cGMP confirm. • Machine's basic construction with separate compression zone and drive zone and electric controls zone. • Fast Cleaning and Changeover capability. • Stainless Steel and Acrylic Glass Surrounding. • Easy to Operate and Maintenance.  Salient Features : • Design Conforming to cGMP standards. • Contact parts SS 316 and non contact parts SS 304. • TabXpress-IV is high speed double sided tablet press with internal gear drive, pre compression and suitable for medium size batch production and offered in three model "D" , "B" & "BB" Tooling • Simple and Convenient Operation, Changeover, Cleanliness, Operator Protection and Easy to Maintenance. • Pre-Compression System to improve tablet quality • All Controls like tablet thickness, weight adjustment, Pre-press adjustment are in front of the machine and outside the compression zone • Turret Drive from Closed Gearbox through Internal Helical Gearing with Continuous Lubrication. • Electro Magnetic Clutch Drive for Safety, Ease and Maintains Free operation. • A C Frequency drive for Turret Motor and Feeder Motor. • Force Feeder for Powder Feeding with Bottom side drive. • Fast changeover and Easy cleaning designed with Easy removal Weight adjustment sector. • Upper guard with Hydraulic Cylinder and Lower guard From S.S. 304 fitted Limit switch. • Turret made from Special graded casting and option for 3pc.turret with S.S.316 Diepot. • Hydraulic Power Pack for Pressure Loading & Overloading release. • Auto Lubrication System for Turret gearing and fulcrum pins. • Paint free Tablet Compression zone. • Dust suction nozzle for Controlling Dusting. • Closed Dust free Front Electric Control Panel easy Removal type  Optional Features : • Gravity feeder System. • Powder level sensor in hopper. • During Start and Stop Rejection and Sampling device • Advance PLC controls with Touch Screen interface..  Safety Features : • Interlocked upper guard and Overload relay protection. • Overload pressure release mechanism. • Emergency stop button.
Rapid Mixer Granulator - RMG /High Shear Mixer Granulator-HSMG (High Performance Mixing and Wet Granulation Process Technic) Application & Process : • The High Shear Mixer Granulator used for process of fast dry & wet mixing, homogenizing, humidifying and granulating of the powder in Pharmaceutical, Chemical, Cosmetic, Food, Plastic, General Mixing Industries. • High Shear Mixer Granulator series is characterized by the compact construction, modern design and all the user and maintenance friendly attributes which form the ergonomics design aspects are essential for a wide range of application. • The High Shear Mixer Granulator performs dry mixing & wet granulating by basic design of the special four arm of the mixing impeller and sequences of the mixing process in the cylindrical mixing drum with rounded connection to the base plate, achieve another special effect. The mixing process runs without varying pressure zone in the volume of mixing product. Separately driven multiple choppers can effectively intensify the mixing result in particular when liquid or paste components are added. During humidifying and granulating process of the products the chopper controls and regulates the granular spectrum and structure of the granules according to the product, chopper shape and time. The HSMG system requires only small quantities of granulating liquid or pastes to obtain the required granulate structure. This reduces the amount of drying energy required. Salient Features : • High speed mixing & granulating • Design is cGMP - Current Good Manufacturing Practices compliance • All Product contact parts AISI 316 & non contact parts AISI 304. • Automated maxing and granulating process in single bowl. • High Precision mixing and granulation with Short Batch Time, Problem free Cleaning and Residue Free Discharge. • Unique design with four arm mixing impeller with blade angle to pushing product radically outward. • Chopper blade designed to cuts lumps and make granules. • Dual speed mixing impeller for mixing and intensify chopper for granulating. • Flush fitting discharge plug is electro pneumatically operated. • Air pursing for seal for both shafts. Optional Features : • PLC Controls with HMI touch screen, • Inline Milling at discharge, • Variable speed drive for main impeller and chopper. • Product bowl Jacketing for heating/ cooling and vacuumized mixing process. • Binder adding by spraying system with peristaltic pump. • Material charging by bin loader with IBC. • Flame proof motor and electrical. Safety Features : • Total drive transmission system enclosed • Limit switch installed in the top lid ensure lid is closed • Air pressure switch installed to ensure pressure is in limit. • Limit switch installed at discharge to ensure product container underneath of discharge. • Overload relay Protection and Emergency stop button
Auto Coater High Efficiency and Intelligent Automatic Tablet Film & Sugar Coating Technic  Application & Process : • The Prism's advanced high efficiency automated tablet coating machine is mainly used in pharmaceutical and food industries. Featuring mechatronis and confirming to the requirement of cGMP. It is a high efficiency, energy saving, safe and clean equipment for film and sugar coating of tablets, Pills and candies with organic film, aqueous coating and sugar film etc.  Automatic Tablet Coater is designed for the application of: 1. Film Coating with organic solvent, Enteric Coating and aqueous coating 2. Sugar Coating  Working Principle : • The tablet to be coated make continuous complicated orbital motion the closed rotating Drum under the action of a streamline of Baffles. During the motion coating medium automatically sprays according to the technological process and rational technological parameters, at the same time hot filtered air supplied under a negative pressure. The hot air penetrates through the tablets core layers and is discharged from the bottom of the layers, so that the coating medium sprayed on the surface of the tablet cores will dry rapidly and evenly, thus forming a solid and smooth surface film on tablet. The whole process is finished under the automatic by PLC Controls with touch screen Interface.  Salient Features : • Design is cGMP - Current Good Manufacturing Practices compliance. • All contact parts AISI 316 & non contact parts AISI 304. • Fully automatic film & sugar coating process by PLC Controls with HMI Touch screen. • Flexible batch operations • Complete separation of production and technical area • Extremely user friendly software and operation through PLC • The machine structure made from S.S.304 quality fitted with Closed Drive, Perforated Pan, Washing sink, Inlet air plenum, Exhaust air plenum with Air tight door. • Excellent mixing and tumbling by special design of removable on each sloping face of the pan and anti sliding baffles provided on perforated diagonal face. • Perforated Pan having variable speed through AC frequency Drive. • Pan mouth closed with Stainless steel door with a glass for process visualization. • A stainless steel 316 sinks at bottom of pan for collection of powder with necessary stainless steel piping with tri-clover joints for ease of cleaning during the changeover. • FLP Fluorescent Light is provided for illumination inside the pan • All doors, safety guards and covers are provided with a silicon food grade seals • Automatic Spraying systems provided with Atomized spray Gun, Adjustable spray gun arms, High precise flow peristaltic pump, solution holding tank with pneumatic stirrer. • Front Entry stainless steel arm, with facility to adjust the angle of spray guns is provided. • Inlet air and Exhaust air plenum provided with silicon seal with easy removable for cleaning. • Inlet air and outlet air will be controlled by pneumatic operated damper which is provided on top of the machine and at inlet and outlet duck. • Inlet air and Exhaust air flow controls through AC Frequency drive of both blower. • Inlet Air handling unit made from double screen insulated with puff with inside stainless steel 304 quality and outside powder coated. The Inlet air handling units fitted with Pre filter- 10 micron, Inlet air blower with motor, Dehumiditifier- child water circulation coil, Stainless steel 304 quality Steam/ Electric heat exchanger with fins, Final filter with 5 micron, HEPA filter -0.3 micron. • Exhaust Air handling unit provided with dust collection system with 5 micron filter or wet scrubber and exhaust blower. The Exhaust air dust collector unit is made from .S.S.304 Quality. • Treatment of exhaust air for pollution free operation. • The Entire Inlet Air handler and Exhaust air unit to be install in technical service area. • Tablet discharging facility will be through the special diverter assembly • Advanced CIP /WIP System is provided for pan internal by spraying ball and outer washing by spraying nozzle both side. The complete system will operate and controls through machine PLC for washing cycle for Plain water, Detergent, Hot water, Distilled water and Drying by air. • All motor are flam proof/ Explosion proof provided. • Advance PLC Controls system with HMI- color Touch screen provided of Allen Bradley/ Siemens make for complete automatic coating process and batch data receipt management . Also option for SCADA connectivity with FDA 21 CFR part 11 • The machine instruction manual and Validation document provided for DQ, FAT, IQ, SAT and OQ with test and calibration certificate.  Optional Features : • Interchangeable Pan • Solid Pan for confectionery products. • Wet Scrubber • Dry Dust Collector • Dehumidifier • Steam or Electric Heat Exchanger. • Tablets charging by bin loader. • SCADA Connectivity.
(Roll Compactor - Dry Compaction) Powder Dry Granulation Process. Application & Process : The Roll Compactor machine is used for increased bulk density, making granules, dust free processing and reducing particle size of pharmaceutical ingredients in pharmaceutical industry, in food as well as chemical industry for densification and granulation of powder. The material in form of powder passes through the two counter rotating rolls of roller compactor under very high pressure. As the volume decreases through the region of maximum pressure, the material is formed into a solid compact sheet or flakes of ingredients. These flakes or compact sheet of ingredients are reduced in size to obtain the desired grain size. The machine takes extra care to prevent the generation of fine during this process. New Design Features : • Design is cGMP - Current Good Manufacturing Practices compliance • All Product contact parts AISI 316 & non contact parts AISI 304. • To achieve maximum bulk density and output by various type of rolls. • Available different type of rolls - 1. Plain 2.Corrugated 3.Knurled. • Machine fitted with Corrugated rolls. • Option available for Hydraulically operated Uniform force distribution system can be provided for produce granules equal quality • Option available for the compacting roll can be designed to provide with water cooling system.. • A C Frequency Variable Speed Drive for Auger • Top and bottom scrapper of the roll to scrape off powder sticking on the roll. • Enclosed drive with heavy duty gear box and motor for roll and auger/ feeder. • The hopper and auger/ feeder assembly is lifted by hydraulically for easy cleaning & dismantling. Optional Features : • Option for Uniform force system by hydraulically for Roller. • Optional Water Cooling system for rolls & hopper. • Inline Granulation with Granulator & sifting • PLC Controls with HMI touch screen. • Automatic loading by Vacuum Transfer system. • Flame Proof Electrical. • AC frequency drive for Roller. Safety Features : • Limit switch for chamber, Slip clutch at drive of auger. • Overload relay & Emergency stop.
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